20 beste vacatures voor de functie van end project in zoeterwoude dorp (nieuwe medewerkers gezocht)

PhD candidate Genetic Susceptibility in Stem Cell-Derived Organoid Safety Testing
Universiteit Leiden —Leiden
- € 3.059 - € 3.881 per maand
- Fulltime
- Doctor
- Schrijfvaardigheden
- Engels
Postdoctoral Researcher position on Increasing the visibility of public engagement for OS monitoring
Universiteit Leiden —Leiden
- € 4.728 per maand
- Parttime
- Hybride werken
- Doctor
- Engels
- Onderzoek
- Flexibele werkuren
PhD Position on "Mental disorders as harmful stable states"
Universiteit Leiden —Leiden
- € 3.059 - € 3.881 per maand
- Fulltime
- Hybride werken
- Doctor
- Engels
- Master
- Flexibele werkuren
PhD Candidate in Prospective Sustainability Assessment of Europe's Steel Transition
Universiteit Leiden —Leiden
- € 3.059 - € 3.881 per maand
- Fulltime
- Hybride werken
- Doctor
- Engels
- Onderzoek
PhD position: Operando X-ray spectroscopy on electrocatalytic interfaces (1.0 FTE)
Universiteit Leiden —Leiden
- € 3.059 - € 3.881 per maand
- Fulltime
- Doctor
- Engels
- Master
9 dagen
PhD Position on early colonial North America
Universiteit Leiden —Leiden
- € 3.089 - € 3.881 per maand
- Parttime
- Doctor
- Engels
- Onderzoek
PhD position in modeling the mechanical regulation of plant development and regeneration (1.0 FTE)
Universiteit Leiden —Leiden
- € 3.204 - € 4.051 per maand
- Fulltime
- Doctor
- Schrijfvaardigheden
- Engels
- Flexibele werkuren
1 dag
PhD candidate (Anthropological Linguistics, Descriptive Linguistics)
Universiteit Leiden —Leiden
- € 3.059 - € 3.881 per maand
- Fulltime
- Doctor
- Engels
- Master
Scientific Programmer / Post-Doctoral Researcher on Project Hippocampus: The Future of OpenML
Universiteit Leiden —Leiden
- € 3.546 - € 5.538 per maand
- Parttime
- Doctor
- Informatica
- Onderzoek
- Werk vanuit huis
- Flexibele werkuren
9 dagen
Learning & Talent Development Specialist (Temporary, 12 months)
ASICS —Hoofddorp
- Hybride werken
- Engels
- Kantoor
- Projectmanagement
Junior Research Software Engineer for Sustainability Science - Full Stack
Universiteit Leiden —Leiden
- € 3.708 - € 5.057 per maand
- Fulltime
- Hybride werken
- Onderzoek
- Master
- SQL
Product Marketing Manager – Europe Equipment Portfolio, Microelectronics and Data Center
Ecolab Inc. —Leiden
- Verkoopervaring
- Engineering
- Master
PhD Position in Smart Sensing and Monitoring of Railway Embankment
TU Delft —Delft
- € 3.059 - € 3.881 per maand
- Online sollicitatie
- Doctor
- Engels
- Master
- Flexibele werkuren
Postdoc in Open Quantum System Dynamics, Department of Quantum Nanosciene, TU Delft (ERC-Funded)
TU Delft —Delft
- € 3.546 - € 5.538 per maand
- Online sollicitatie
- Doctor
- Master
- Analytisch vermogen
Vacature: Jr. Project Manager – Strategy & Transformation Office Group Finance - View vacancy
Bekijk bedrijf: NN Group —Den Haag
- € 3.891 - € 5.188 per maand
- Fulltime
- Engels
- Financiën
- Projectmanagement
3 uur
PhD Position on Assessing Private Climate Change Adaptation Effectiveness and Limits
TU Delft —Delft
- € 3.059 - € 3.881 per maand
- Parttime
- Doctor
- Engels
- Master
- Flexibele werkuren
Group Internal Audit & Control
ACOMO N.V. —Rotterdam
- Fulltime
- Hybride werken
- Engels
- Master
- Analytisch vermogen
Snel solliciteren
10 dagen
PhD Position Modelling and Optimization of Processes to Recycle Low-grade Biogenic Waste
TU Delft —Delft
- € 3.059 - € 3.881 per maand
- Online sollicitatie
- Doctor
- Schrijfvaardigheden
- Master
14 dagen
Sales Manager Aftermarket Sales
NEM Energy —Zoeterwoude
- € 4.800 - € 5.500 per maand
- Fulltime
- Hybride werken
- Verkoopervaring
- Engels
- Bachelor
Snel solliciteren
PhD Position Distribution Systems Flexible Operation under Uncertain and Incomplete Information
TU Delft —Delft
- € 3.059 - € 3.881 per maand
- Online sollicitatie
- Doctor
- Engels
- Master
- Flexibele werkuren

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PhD candidate Genetic Susceptibility in Stem Cell-Derived Organoid Safety Testing

Universiteit Leiden -
Leiden

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Vacaturegegevens

Fulltime
€ 3.059 - € 3.881 per maand

Secundaire arbeidsvoorwaarden

Sabbatical

Kwalificaties

Doctor
Schrijfvaardigheden
Engels
Onderzoek
Master
Bachelor
Farmacie

Volledige vacaturetekst

Job requisition Id: 16775

Job type: PhD positions

Contract hours min: 38

Contract hours max: 38

Location: Leiden

Applying is possible until: 21 augustus 2026

Teaser Text

The Faculty of Science and the Division of Cell Systems and Drug Safety is looking for a:

PhD candidate Genetic Susceptibility in Stem Cell-Derived Organoid Safety Testing

Why do people respond differently to harmful substances, and why are some individuals more sensitive to organ damage? This PhD project addresses these fundamental questions by investigating human toxicodynamic variability; the differences in how cells respond to chemical stress. These differences are partly driven by genetic variation, which influences cellular pathways involved in toxicity. Understanding this variation is essential for developing future safety testing strategies that reflect real human diversity.

What you will do

In this project, you will work with human induced pluripotent stem cells (iPSCs) and primary cells derived from donors with different (genetic) backgrounds. By differentiating these stem cells into organ specific cell types and 3D organoids together with CRISPR technology, you will study how genetic variants shape cellular responses to chemical exposure. Combined with advanced detection tools that visualize cellular stress responses, this approach allows you to map how individual’s background translate into toxicodynamic variability.

The project serves as a proof of concept for integrating human variability into next‑generation in vitro safety testing. The knowledge generated will contribute to more accurate risk estimation and support the development of chemical safety assessments that better reflect human diversity.

What you bring

MSc in (Bio)-pharmaceutical Sciences, Biomedical Sciences or Biology
Expertise in (human) induced pluripotent stem cell culture, 3D in vitro systems, molecular and cell biology, gene editing, microscopy, cell signaling
Interest in bioinformatics
Written and oral proficiency in English
Excellent scientific writing skills
Enthusiastic and ambitious
Independent thinker
Team player

Where you will work

Curiosity and passion for science are what connect our people: the desire to know, understand, interpret, explain and create. Our mission is to provide excellent teaching and research across the full breadth of the sciences, contributing to solutions for major societal challenges. Our eight institutes, ranging from mathematics, computer science, astronomy, physics, chemistry, and biopharmaceutical sciences to biology and environmental sciences, along with the Lorentz Center and the Hortus botanicus, form the backbone of our faculty and have a strong mutual interconnectedness.

We work in a safe, stimulating and international environment where people work and study with pleasure and passion, and where building connections and collaboration, both within and beyond the faculty, are a clear choice. The faculty has over 2,700 staff members and more than 6,000 students enrolled in nine bachelor's and fifteen master's programmes. We are located in the heart of the Bio Science Park, one of Europe’s largest science parks, where academia and industry meet.

For more information, see: https://www.universiteitleiden.nl/en/science

What we offer

We offer a full-time (1.0 FTE, 38 hours) 4-year term position. Salary range from € 3.059,- to € 3.881,- gross per month (PhD student, pay scale P) in accordance with the Collective Labour Agreement for Dutch Universities. We aim to employ more women in areas where they are underrepresented. Women are therefore especially invited to apply.

Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses (8.3 %), training and career development and sabbatical leave. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. Candidates from outside the Netherlands may be eligible for a substantial tax break. For more information about employment conditions, see https://www.universiteitleiden.nl/en/working-at/job-application-procedure-and-employment-conditions

All our PhD students are embedded in the Leiden University Graduate School of Science. Our graduate school offers several PhD training courses at three levels: professional courses, skills training and personal effectiveness. In addition, advanced courses to deepen scientific knowledge are offered by the research school.

What we value

Promoting an inclusive community is central to Leiden University’s values and vision. We strive to be an open community in which all students and staff members feel valued and respected, and are able to fully develop themselves. We consider an inclusive academic environment, where students and staff can share their experiences and viewpoints, to be essential for the development of talent.

Want to apply or find out more?

Enquiries can be made to Dr. Marije Niemeijer ([email protected]; +31 71 5275919). If you have any questions about the procedure, please contact the secretariat of the Division of Cell Systems and Drug Safety, Marjolijn Lugthart ([email protected]; +31 71 5276270). Information about the faculty of science can be found at http://www.science.leidenuniv.nl/index.php/english/ and about Leiden University at http://www.vacancies.leiden.edu/ .

To apply for this vacancy, please submit your application online via the blue button in our application system.

Please ensure that you upload the following additional document quoting the vacancy number:

Motivation letter
Curriculum Vitae
The transcripts of your BSc and MSc studies to date
A copy of your (draft) Master’s thesis
Preferably 2 reference letters

Only applications received before 21 August 2026 can be considered.

Starting date: fall 2026, flexible.

Information at a Glance

Faculty / Unit: The Faculty of Science

Contact with (Name + position): D. Marije Niemeijer, Assistant Professor

Contact Email address: [email protected]

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Verfijn je zoekopdracht

end project vacatures in zoeterwoude dorp

PhD candidate Genetic Susceptibility in Stem Cell-Derived Organoid Safety Testing

Postdoctoral Researcher position on Increasing the visibility of public engagement for OS monitoring

PhD Position on "Mental disorders as harmful stable states"

PhD Candidate in Prospective Sustainability Assessment of Europe's Steel Transition

PhD position: Operando X-ray spectroscopy on electrocatalytic interfaces (1.0 FTE)

PhD Position on early colonial North America

PhD position in modeling the mechanical regulation of plant development and regeneration (1.0 FTE)

PhD candidate (Anthropological Linguistics, Descriptive Linguistics)

Scientific Programmer / Post-Doctoral Researcher on Project Hippocampus: The Future of OpenML

Learning & Talent Development Specialist (Temporary, 12 months)

Junior Research Software Engineer for Sustainability Science - Full Stack

Product Marketing Manager – Europe Equipment Portfolio, Microelectronics and Data Center

PhD Position in Smart Sensing and Monitoring of Railway Embankment

Postdoc in Open Quantum System Dynamics, Department of Quantum Nanosciene, TU Delft (ERC-Funded)

Vacature: Jr. Project Manager – Strategy & Transformation Office Group Finance - View vacancy

PhD Position on Assessing Private Climate Change Adaptation Effectiveness and Limits

Group Internal Audit & Control

PhD Position Modelling and Optimization of Processes to Recycle Low-grade Biogenic Waste

Sales Manager Aftermarket Sales

PhD Position Distribution Systems Flexible Operation under Uncertain and Incomplete Information

Ik wil de nieuwste vacature-alerts ontvangen voor de functie van end project in zoeterwoude dorp

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